Do you know the long-term effects antidepressant medications have on the brain? Have you considered other treatment options, especially if your tried multiple antidepressants with no real relief from your symptoms? It is important to know all of your treatment options, especially when treating a serious condition like depression. While antidepressants are certainly necessary and work for some people, other forms of treatment should be considered, such as transcranial magnetic stimulation (TMS). TMS is the most advanced form of depression treatment without any of the systemic side effects associated with antidepressants.